PRR Project

Summary

The hired researcher will conduct research in the field of biochemistry and biomedicine, focused on the domains indicated above - Molecular biology; Molecular Mechanisms of Disease; Molecular genetics; Transcriptomics, Proteomics, Metabolomics and Functional Genomics; Intracellular Traffic, Receptors and Membrane Biology – which are central to BioISI’s Vision and Scientific Strategycreating synergies with biological chemistry, biophysics, computational and molecular biology, forging interdisciplinary approaches to unravel molecular complexities.The hired researcher will contribute to the ongoing lines of research that include the identification of disease-causing pathways/networks, of key disrupted genes and how these pathways/networks are impacted by the environment and lifestyle to design novel therapeutic strategies. The main areas of research will be mechanisms of disease, personalized medicine and novel therapies, with a focus on conformational disorders.The hired researcher will integrate one of the areas of highest internationalization profile within BioISI – that focus on understanding complex mechanisms of human disease at the scale of the cell, the tissue, the organism – with the capacity to link to drug development strategies, the study of molecular interactions and data analysis from a perspective of big data, thus bridging to Systems Biology and Bioinformatics.  The researcher is expected to be fully engaged in all the activities and duties associated with the position, including: (1) Conduct innovative, high-impact, internationally recognized research in biomedicine aligned with the above described goals; (2) Interact and collaborate with multidisciplinary teams across campus to advance programs from early discovery to applied outputs; (3) Apply to competitive calls at the national/international level for securing external funding; (4) Publish research findings in leading scientific journals; (5) Perform advanced training, supervision and mentoring of graduate students; (6) Take active part in outreach activities.The recruited fellow will thus reinforce the components of Biomedicine and strengthen collaboration networks with various groups inside and outside BioISI and DQB.