PRR Project

Summary

The NOVA Institute for Medical Systems Biology (NIMSB) will hire a skilled and motivated Assistant Researcher with a strong background in Cell Biology, Regenerative Biology, and Regenerative Medicine. The successful candidate will lead innovative research projects focused on zebrafish models and/or human tissues and organoids to advance our understanding and capabilities in tissue regeneration and disease modelling. Key Responsibilities:1) Innovative Research: Lead and conduct cutting-edge research projects in regenerative biology, focusing on the use of micro-physiological systems, such as organoids, and zebrafish models. Develop and execute experimental protocols to study cellular and molecular mechanisms of tissue regeneration.2) Cell Biology: Apply advanced techniques in cell biology to investigate cellular responses and interactions during regeneration processes. Utilize methods such as cell culture, microscopy, flow cytometry, and molecular biology assays.3) Organoid Models: Develop and refine organoid models as in vitro systems for studying regenerative processes. Work on the cultivation, differentiation, and analysis of organoids derived from various cell types.4) Zebrafish Experimental System: Utilize zebrafish as a model organism for in vivo studies of tissue regeneration. Perform genetic, pharmacological, and surgical manipulations to study regenerative phenomena in zebrafish.5) Collaborative Research: Collaborate with internal teams and external partners, including interdisciplinary groups, to advance research projects. Participate in joint ventures that bridge the gap between basic science and translational regenerative medicine.6) Data Analysis and Reporting: Analyse experimental data using statistical methods. Prepare and present research findings at internal meetings and scientific conferences. Contribute to the writing of research papers for publication in high impact peer-reviewed journals.7) Mentorship and Supervision: Mentor and supervise junior researchers and students. Provide guidance in experimental design, data analysis, and scientific writing.8) Funding: Contribute to the development of research proposals and funding applications. Scientific Profile:1) PhD in Cell Biology, Developmental Biology, or a related field.2) Minimum of 10 years postdoctoral experience in regenerative biology, preferably with expertise in organoid technology or zebrafish models.3) Demonstrated experience with tissue culture, especially the cultivation and differentiation of stem cells into organoids.4) Proficiency in molecular biology techniques, including but not limited to qRT-PCR, Western blotting, immuno-histochemistry, and gene editing tools.5) Publication record in regenerative biology or related disciplines.6) Excellent analytical and problem-solving skills.7) Ability to work independently as well as part of a team.8) Strong communication and interpersonal skills. Rationale for Hiring:The field of Regenerative Medicine is rapidly advancing, with the use of complex human organoids promising great translational potential and the use of animal models that have remarkable regenerative capabilities. Hiring an Assistant Researcher with expertise in at least one of these areas is crucial for NIMSB to stay competitive and innovative in the global research landscape. This position will bridge the gap between fundamental regenerative biology and translational medicine, aiming to discover novel therapeutic approaches for regenerative medicine and tissue engineering. The Assistant Researcher contributions will be essential in developing next-generation treatments for a variety of diseases and injuries where regenerative medicine can offer significant improvements in patient outcomes.By integrating the study of human organoids, which recapitulate the architecture and function of real tissues, with the regenerative power of zebrafish, this role will push the boundaries of current knowledge and contribute to the development of cutting-edge therapies. This strategic hire will strengthen NIMSB research capacity, enable new collaborative projects, secure research funding, and enhance the institutional reputation as a leader in systems biology and regenerative medicine research.